Field estimates of reproductive success in a model insect: behavioural surrogates are poor predictors of fitness

Understanding, and therefore measuring, factors that determine fitness is a central problem in evolutionary biology. We studied a natural population of Coenagrion puella (Odonata: Zygoptera) over two entire breeding seasons, with over a thousand individuals uniquely marked and genotyped, and all mating events at the rendezvous site recorded. Using a parentage analysis, fitness of individuals in the first generation was quantified as the numbers of offspring that survived to maturity. Although mating behaviour can be predicted by environmental and demographical variables, the numbers of mature offspring produced (fitness) cannot, and crucially, are poorly correlated with behavioural observations of mating. While fitness of both sexes was positively related to mating behaviour and to female’s ectoparasite burden, these behavioural observations explained little more variance in offspring production than environmental and demographical variables. Thus, we demonstrate that behavioural measures of reproductive success are not necessarily reliable estimates of fitness in natural populations

Measurement of Particle Parameters in Thermal Spray Systems

Particle parameters are important in the optimization of plasma and flame spray processes that involve fine powders. Such processes include plasma and flame spraying, spheroidizing, and chemical processes in which the material is introduced in the form of fine powders or the final product is in the form of a fine powder, e.g. plasma synthesis of ceramics. To fully characterize the particle flow field, it is necessary to measure the particle size, velocity, and number density. In many cases, it is necessary to measure simultaneously several parameters that are strongly coupled such as particle size and temperature, or size and velocity. In this paper we will describe a laser based measurement technique for simultaneously obtaining the in-flight size, velocity, and temperature of small particles entrained in a flow field

Biomechanical Analysis of Treadmill Locomotion on the International Space Station

Treadmill locomotion exercise is an important aspect of ISS exercise countermeasures. It is widely believed that an optimized treadmill exercise protocol could offer benefits to cardiovascular and bone health. If training heart rate is high enough, treadmill exercise is expected to lead to improvements in aerobic fitness. If impact or bone loading forces are high enough, treadmill exercise may be expected to contribute to improved bone outcomes. Ground-based research suggests that joint loads increase with increased running speed. However, it is unknown if increases in locomotion speed results in similar increases in joint loads in microgravity. Although data exist regarding the biomechanics of running and walking in microgravity, a majority were collected during parabolic flight or during investigations utilizing a microgravity analog. The Second Generation Treadmill (T2) has been in use on the International Space Station (ISS) and records the ground reaction forces (GRF) produced by crewmembers during exercise. Biomechanical analyses will aid in understanding potential differences in typical gait motion and allow for modeling of the human body to determine joint and muscle forces during exercise. By understanding these mechanisms, more appropriate exercise prescriptions can be developed that address deficiencies. The objective of this evaluation is to collect biomechanical data from crewmembers during treadmill exercise prior to and during flight. The goal is to determine if locomotive biomechanics differ between normal and microgravity environments and to determine how combinations of subject load and speed influence joint loading during in-flight treadmill exercise. Further, the data will be used to characterize any differences in specific bone and muscle loading during locomotion in these two gravitational conditions. This project maps to the HRP Integrated Research Plan risks including Risk of Bone Fracture (Gap B15), Risk of Early Onset Osteoporosis Due to Spaceflight (Gap B15), Risk of Impaired Performance Due to Reduced Muscle Mass, Strength, and Endurance (Gaps M3, M4, M6, Ml, M8, M9) and Risk of reduced Physical Performance Capabilities Due to Reduce Aerobic Capacity (Gaps M7, M8, M9)

Development of a Ground-Based Analog to the Advanced Resistive Exercise Device Aboard the International Space Station

NASA and Wyle engineers constructed a Horizontal Exercise Fixture (HEF) that was patented in 2006. Recently modifications were made to HEF with the goal of creating a device that mimics squat exercise on the Advanced Resistive Exercise Device (ARED) and can be used by bed rest subjects who must remain supine during exercise. This project posed several engineering challenges, such as how best to reproduce the hip motions (we used a sled that allowed hip motion in the sagittal plane), how to counterweight the pelvis against gravity (we used a pulley and free-weight mechanism), and how to apply large loads (body weight plus squat load) to the shoulders while simultaneously supporting the back against gravity (we tested a standard and a safety bar that allowed movement in the subject s z-axis, both of which used a retractable plate for back support). METHODS An evaluation of the HEF was conducted with human subjects (3F, 3M), who performed sets of squat exercises of increasing load from 10-repetition maximum (RM) up to 1-RM. Three pelvic counterweight loads were tested along with each of the two back-support squat bars. Data collection included 3-dimensional ground reaction forces (GRF), muscle activation (EMG), body motion (video-based motion capture), and subjective comments. These data were compared with previous ground-based ARED study data. RESULTS All subjects in the evaluation were able to perform low- to high-loading squats on the HEF. Four of the 6 subjects preferred a pelvic counterweight equivalent to 60 percent of their body weight. Four subjects preferred the standard squat bar, whereas 2 female subjects preferred the safety bar. EMG data showed muscle activation in the legs and low back typical of squat motion. GRF trajectories and eccentric-concentric loading ratios were similar to ARED. CONCLUSION: Squat exercise performed on HEF approximated squat exercise on ARED

Implementation aspects of list sphere decoder algorithms for MIMO-OFDM systems

A list sphere decoder (LSD) can be used to approximate the optimal maximum a posteriori (MAP) detector for the detection of multiple-input multiple-output (MIMO) signals. In this paper, we consider two LSD algorithms with different search methods and study some algorithm design choices which relate to the performance and computational complexity of the algorithm. We show that by limiting the dynamic range of log-likelihood ratio, the required LSD list size can be lowered, and, thus, the complexity of the LSD algorithm is decreased. We compare the real and the complex-valued signal models and their impact on the complexity of the algorithms. We show that the real-valued signal model is clearly the less complex choice and a better alternative for implementation. We also show the complexity of the sequential search LSD algorithm can be reduced by limiting the maximum number of checked nodes without sacrificing the performance of the system. Finally, we study the complexity and performance of an iterative receiver, analyze the tradeoff choices between complexity and performance, and show that the additional computational cost in LSD is justified to get better soft-output approximation.TekesFinnish Funding Agency for Technology and InnovationNokiaNokia Siemens Networks (NSN)ElekrobitUninor

Development of a High Fidelity Dynamic Module of the Advanced Resistive Exercise Device (ARED) Using Adams

NASA's Digital Astronaut Project (DAP) implements well-vetted computational models to predict and assess spaceflight health and performance risks, and enhance countermeasure development. DAP provides expertise and computation tools to its research customers for model development, integration, or analysis. DAP is currently supporting the NASA Exercise Physiology and Countermeasures (ExPC) project by integrating their biomechanical models of specific exercise movements with dynamic models of the devices on which the exercises were performed. This presentation focuses on the development of a high fidelity dynamic module of the Advanced Resistive Exercise Device (ARED) on board the ISS. The ARED module, illustrated in the figure below, was developed using the Adams (MSC Santa Ana, California) simulation package. The Adams package provides the capabilities to perform multi rigid body, flexible body, and mixed dynamic analyses of complex mechanisms. These capabilities were applied to accurately simulate: Inertial and mass properties of the device such as the vibration isolation system (VIS) effects and other ARED components, Non-linear joint friction effects, The gas law dynamics of the vacuum cylinders and VIS components using custom written differential state equations, The ARED flywheel dynamics, including torque limiting clutch. Design data from the JSC ARED Engineering team was utilized in developing the model. This included solid modeling geometry files, component/system specifications, engineering reports and available data sets. The Adams ARED module is importable into LifeMOD (Life Modeler, Inc., San Clemente, CA) for biomechanical analyses of different resistive exercises such as squat and dead-lift. Using motion capture data from ground test subjects, the ExPC developed biomechanical exercise models in LifeMOD. The Adams ARED device module was then integrated with the exercise subject model into one integrated dynamic model. This presentation will describe the development of the Adams ARED module including its capabilities, limitations, and assumptions. Preliminary results, validation activities, and a practical application of the module to inform the relative effect of the flywheels on exercise will be discussed

Implementation of a High Throughput Soft MIMO Detector on GPU

Multiple-input multiple-output (MIMO) significantly increases the throughput of a communication system by employing multiple antennas at the transmitter and the receiver. To extract maximum performance from a MIMO system, a computationally intensive search based detector is needed. To meet the challenge of MIMO detection, typical suboptimal MIMO detectors are ASIC or FPGA designs. We aim to show that a MIMO detector on Graphic processor unit (GPU), a low-cost parallel programmable co-processor, can achieve high throughput and can serve as an alternative to ASIC/FPGA designs. However, careful architecture aware software design is needed to leverage the performance offered by GPU. We propose a novel soft MIMO detection algorithm, multi-pass trellis traversal (MTT), and show that we can achieve ASIC/FPGA-like performance and handle different configurations in software on GPU. The proposed design can be used to accelerate wireless physical layer simulations and to offload MIMO detection processing in wireless testbed platforms.NokiaNokia Siemens Networks (NSN)Texas InstrumentsXilinxNational Science Foundatio

Solving the Shortest Vector Problem in Lattices Faster Using Quantum Search

By applying Grover's quantum search algorithm to the lattice algorithms of Micciancio and Voulgaris, Nguyen and Vidick, Wang et al., and Pujol and Stehl\'{e}, we obtain improved asymptotic quantum results for solving the shortest vector problem. With quantum computers we can provably find a shortest vector in time $2^{1.799n + o(n)}$, improving upon the classical time complexity of $2^{2.465n + o(n)}$ of Pujol and Stehl\'{e} and the $2^{2n + o(n)}$ of Micciancio and Voulgaris, while heuristically we expect to find a shortest vector in time $2^{0.312n + o(n)}$, improving upon the classical time complexity of $2^{0.384n + o(n)}$ of Wang et al. These quantum complexities will be an important guide for the selection of parameters for post-quantum cryptosystems based on the hardness of the shortest vector problem.Comment: 19 page

A High Throughput Configurable SDR Detector for Multi-user MIMO Wireless Systems

Spatial division multiplexing (SDM) in MIMO technology significantly increases the spectral efficiency, and hence capacity, of a wireless communication system: it is a core component of the next generation wireless systems, e.g. WiMAX, 3GPP LTE and other OFDM-based communication schemes. Moreover, spatial division multiple access (SDMA) is one of the widely used techniques for sharing the wireless medium between different mobile devices. Sphere detection is a prominent method of simplifying the detection complexity in both SDM and SDMA systems while maintaining BER performance comparable with the optimum maximum-likelihood (ML) detection. On the other hand, with different standards supporting different system parameters, it is crucial for both base station and handset devices to be configurable and seamlessly switch between different modes without the need for separate dedicated hardware units. This challenge emphasizes the need for SDR designs that target the handset devices. In this paper, we propose the architecture and FPGA realization of a configurable sort-free sphere detector, Flex-Sphere, that supports 4, 16, 64-QAM modulations as well as a combination of 2, 3 and 4 antenna/user configuration for handsets. The detector provides a data rate of up to 857.1 Mbps that fits well within the requirements of any of the next generation wireless standards. The algorithmic optimizations employed to produce an FPGA friendly realization are discussed.Xilinx Inc.National Science Foundatio

Electronic consultations (E-consults) and their outcomes: a systematic review

OBJECTIVE: Electronic consultations (e-consults) are clinician-to-clinician communications that may obviate face-to-face specialist visits. E-consult programs have spread within the US and internationally despite limited data on outcomes. We conducted a systematic review of the recent peer-reviewed literature on the effect of e-consults on access, cost, quality, and patient and clinician experience and identified the gaps in existing research on these outcomes. MATERIALS AND METHODS: We searched 4 databases for empirical studies published between 1/1/2015 and 2/28/2019 that reported on one or more outcomes of interest. Two investigators reviewed titles and abstracts. One investigator abstracted information from each relevant article, and another confirmed the abstraction. We applied the GRADE criteria for the strength of evidence for each outcome. RESULTS: We found only modest empirical evidence for effectiveness of e-consults on important outcomes. Most studies are observational and within a single health care system, and comprehensive assessments are lacking. For those outcomes that have been reported, findings are generally positive, with mixed results for clinician experience. These findings reassure but also raise concern for publication bias. CONCLUSION: Despite stakeholder enthusiasm and encouraging results in the literature to date, more rigorous study designs applied across all outcomes are needed. Policy makers need to know what benefits may be expected in what contexts, so they can define appropriate measures of success and determine how to achieve them. Informatics Association 2019. This work is written by US Government employees and is in the public domain in the US